3 Minutes
The scalpel doesn’t just cut tissue. It slices through routines, rhythms and the fragile quiet of a person’s mind. Anxiety does not wait for the patient to be under anesthesia. It arrives at the pre-op holding room, sits beside the IV stand and quietly rewrites the recovery script.
A new study in JAMA Network Open casts a stark light on that unwelcome passenger. Researchers followed 306 adults aged 60 and older who were scheduled for heart, cancer or orthopedic surgery. Instead of treating preoperative care as a checklist of labs and fasting rules, the team tested whether building mental resilience before the operation changes outcomes after it.
"Surgical stress can amplify symptoms of anxiety and depression and affect recovery and overall health," said lead author Joanna Abraham in a press statement. The trial split participants into two paths. One group received only self-guided educational materials. The other took part in 8 to 12 telephone sessions with a trained behavioral health professional—social workers and mental health counselors—and also received personalized medication reviews by pharmacists and physicians, who helped adjust risky or unnecessary drugs.

The results were subtle, but meaningful. Three months after surgery, patients who had mental-health sessions and medication consultations showed a 2.2 to 2.5 point reduction in anxiety and depression scores on a 48-point scale compared with the education-only group. Older adults undergoing cancer surgery benefited the most: their scores were nearly five points lower than those in the control arm. Patients reported that the additional attention from clinicians and pharmacists—especially suggestions to discontinue unnecessary medications—was helpful and reassuring.
Preparing the mind before surgery can have measurable, clinically meaningful effects on recovery. Short sessions on coping strategies, worry management and medication safety aren’t glamorous. They are practical. They are cheap compared with the cost of complications and longer hospital stays. And for older patients, who often carry both physical frailty and a complex medication list, the combination of mental support and careful deprescribing appears especially potent.
So what should change? Hospitals can no longer treat emotional readiness as an afterthought. Pre-op pathways that add a few counseling calls and a pharmacist review could be integrated into surgical planning—particularly for high-risk, older patients or those facing cancer operations. The next step is clear: scale and test these programs across diverse health systems to see if the small score changes translate into fewer complications, shorter stays and better long-term function.
Surgeons prepare the body. Anesthesiologists steady the physiology. But who prepares the patient’s mind? That question may determine how quickly someone walks out of the hospital and how well they return to life afterward.




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